Impact of the Frequency of MDC Use on Clinical Outcomes in Type 2 Diabetes

Objectives

To compare the efficacy in achieving the fasting self-monitoring plasma glucose (SMPG) Target of 90-130 mg/dL, between two insulin glargine titration methods: My Dose Coach^TM app with remote real-time settings (MDC) and conventional strategy (CS) with face-to- face insulin dose modifications every 2 weeks.

In this analysis of the impact of My Dose Coach^TM use…

Executive Summary

Results

A) Proportion of My Dose Coach^TM users
achieving FBG target

B) Time to FBG target achievement

C) FBG change, in different app usage
frequency groups

Conclusion

Higher My Dose Coach^TM usage was associated with:

Better FBG target achievement

Shorter time to FBG target

Greater reduction from baseline FBG

Hypoglycemia risk did not change with increased frequency of My Dose Coach^TM usage

People with T2D initiating BI using My Dose Coach^TM >3 days/ week during titration had better glycemic outcomes than those with lower usage, with no increase in hypoglycemia
These results suggest that use of My Dose Coach^TM may help people with T2D manage their disease by appropriately titrating their BI dose to achieve glycemic targets; such a personal application may also encourage patient participation in managing their condition

Method

This retrospective observational cohort analysis included people with T2D who were registered for My Dose Coach^TM by their HCP between 8/1/2018 – 4/30/2020 and received BI
Study outcomes included change in FBG, change in insulin dose, occurrence of hypoglycemia (defined as FBG below the HCP defined hypoglycemia cut-off per the titration plan), usage of My Dose Coach^TM, percentage of users achieving FBG target, and time to achieving FBG target
Users were trained to record FBG and administered BI doses directly in My Dose Coach^TM. Users with an activated care plan and ≥ 2 FBG observations spanning at least 2 weeks (active users) were selected for analysis
Users who logged ≥ 3 consecutive FBG measurements within their prescribed target range were defined as reaching titration target (specified by the HCP during care plan creation)

Reference