Science at Sanofi

This evidence-based 3.17-minute video explores how uncontrolled atopic dermatitis creates cumulative disease burden beyond visible skin manifestations. Discover the hidden burden—psychological, social, and systemic impacts often overlooked—and the long-term implications of chronic inflammation. Learn to recognize progression patterns and the critical importance of early intervention strategies.

This educational video examines the pathophysiological mechanisms underlying mucus plug formation in asthma and explores their clinical significance in airway obstruction. The presentation addresses how mucus plugging contributes to disease burden and persistent symptoms in asthmatic patients. Healthcare professionals will learn about the cellular and molecular processes involved in mucus hypersecretion and their impact on patient outcomes.

This poster presentation evaluates the efficacy of dupilumab in treating eosinophilic esophagitis (EoE) in patients weighing ≥15 kg at baseline from the Phase 3 KIDS study.

Study Overview: The analysis examines dupilumab efficacy stratified by previous treatment history, including:

- Prior or current use of swallowed topical corticosteroids (STCs) 
- Concomitant proton pump inhibitor (PPI) treatment 
- History of food elimination diet

The soundbite recording captures Dr. Paller's discussion on factors that contribute to the development of atopic comorbidities in patients with atopic dermatitis. The presentation examines the relationship between AD and associated atopic conditions.