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Aldurazyme®

Aldurazyme®: MPS I long-term enzyme replacement therapy

Access essential insights for MPS I specialists

Register or log in to access valuable resources about Aldurazyme®, a therapy designed to treat the non-neurological manifestations of MPS I. You'll receive the latest updates, educational materials1,10,14,15, and tools to enhance patient care. Sign up now to stay informed and make a difference in your practice.

References

  1. Aldurazyme Smpc Oct 2019.
  2. Early initiation of Aldurazyme® has been shown to influence the natural history of MPS I.
  3. O’Connor P, Wolinsky JS, Confavreux C, et al; for the TEMSO Trial Group. Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N Engl J Med. 2011;365(14):1293-1303.
  4. Confavreux C, O’Connor P, Comi G, et al; for the TOWER Trial Group. Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Neurol. 2014;13(3):247-256.
  5. O’Connor P, Comi G, Freedman MS, et al; for the Teriflunomide Multiple Sclerosis Oral (TEMSO) Trial Group and the MRI-AC in Houston, Texas. Long-term safety and efficacy of teriflunomide: nine-year follow-up of the randomized TEMSO study. Neurology. 2016;86(10):920-930.
  6. Case reports of siblings initiating Aldurazyme at different ages highlight the benefits of early treatment in preventing and slowing disease progression.
  7. Aldurazyme has more than 17 years of established safety and tolerability.
  8. Clinical guidelines recommend maintaining regular infusions to manage MPS I symptoms effectively.
  9. Long-term commitment to Aldurazyme treatment is crucial for optimal patient outcomes.
  10. Regular assessments are key to monitoring patient response to Aldurazyme and ensuring optimal management of MPS I.

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